Early and aggressive ISR with a polymer- and carrier-free drug-coated stent system

The LEADERS FREE trial concluded that the polymer free drug-coated BioFreedom™ stent appeared to be both safer and more effective than bare-metal stents (BMS) with an ISR rate comparable to traditional DES without the need for prolonged DAPT. We implanted 45 BioFreedom™ stents in 34 patients over a...

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Detalles Bibliográficos
Autores principales: Loch, Alexander, Bewersdorf, Jan Philipp, Veeriah, Ramesh Singh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650585/
https://www.ncbi.nlm.nih.gov/pubmed/29054192
http://dx.doi.org/10.1016/j.ihj.2017.03.002
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author Loch, Alexander
Bewersdorf, Jan Philipp
Veeriah, Ramesh Singh
author_facet Loch, Alexander
Bewersdorf, Jan Philipp
Veeriah, Ramesh Singh
author_sort Loch, Alexander
collection PubMed
description The LEADERS FREE trial concluded that the polymer free drug-coated BioFreedom™ stent appeared to be both safer and more effective than bare-metal stents (BMS) with an ISR rate comparable to traditional DES without the need for prolonged DAPT. We implanted 45 BioFreedom™ stents in 34 patients over a 4-month period. 4 patients represented early (106–238 days after the implant procedure) with angina symptoms and severe ISR was detected in all patients. The rate of severe and early ISR detected in our patient population of 11.8% is comparable to that of traditional BMS. Further studies are warranted.
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spelling pubmed-56505852018-09-01 Early and aggressive ISR with a polymer- and carrier-free drug-coated stent system Loch, Alexander Bewersdorf, Jan Philipp Veeriah, Ramesh Singh Indian Heart J Short Communication The LEADERS FREE trial concluded that the polymer free drug-coated BioFreedom™ stent appeared to be both safer and more effective than bare-metal stents (BMS) with an ISR rate comparable to traditional DES without the need for prolonged DAPT. We implanted 45 BioFreedom™ stents in 34 patients over a 4-month period. 4 patients represented early (106–238 days after the implant procedure) with angina symptoms and severe ISR was detected in all patients. The rate of severe and early ISR detected in our patient population of 11.8% is comparable to that of traditional BMS. Further studies are warranted. Elsevier 2017 2017-03-17 /pmc/articles/PMC5650585/ /pubmed/29054192 http://dx.doi.org/10.1016/j.ihj.2017.03.002 Text en © 2017 Published by Elsevier, a division of Reed Elsevier India, Pvt. Ltd. on behalf of Cardiological Society of India. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Short Communication
Loch, Alexander
Bewersdorf, Jan Philipp
Veeriah, Ramesh Singh
Early and aggressive ISR with a polymer- and carrier-free drug-coated stent system
title Early and aggressive ISR with a polymer- and carrier-free drug-coated stent system
title_full Early and aggressive ISR with a polymer- and carrier-free drug-coated stent system
title_fullStr Early and aggressive ISR with a polymer- and carrier-free drug-coated stent system
title_full_unstemmed Early and aggressive ISR with a polymer- and carrier-free drug-coated stent system
title_short Early and aggressive ISR with a polymer- and carrier-free drug-coated stent system
title_sort early and aggressive isr with a polymer- and carrier-free drug-coated stent system
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650585/
https://www.ncbi.nlm.nih.gov/pubmed/29054192
http://dx.doi.org/10.1016/j.ihj.2017.03.002
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