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THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Transporters

The Concise Guide to PHARMACOLOGY 2017/18 provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which...

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Autores principales: Alexander, Stephen PH, Kelly, Eamonn, Marrion, Neil V, Peters, John A, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Sharman, Joanna L, Southan, Christopher, Davies, Jamie A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650669/
https://www.ncbi.nlm.nih.gov/pubmed/29055035
http://dx.doi.org/10.1111/bph.13883
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author Alexander, Stephen PH
Kelly, Eamonn
Marrion, Neil V
Peters, John A
Faccenda, Elena
Harding, Simon D
Pawson, Adam J
Sharman, Joanna L
Southan, Christopher
Davies, Jamie A
author_facet Alexander, Stephen PH
Kelly, Eamonn
Marrion, Neil V
Peters, John A
Faccenda, Elena
Harding, Simon D
Pawson, Adam J
Sharman, Joanna L
Southan, Christopher
Davies, Jamie A
author_sort Alexander, Stephen PH
collection PubMed
description The Concise Guide to PHARMACOLOGY 2017/18 provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide represents approximately 400 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point‐in‐time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.13883/full. Transporters are one of the eight major pharmacological targets into which the Guide is divided, with the others being: G protein‐coupled receptors, ligand‐gated ion channels, voltage‐gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors and enzymes. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid‐2017, and supersedes data presented in the 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature Committee of the Union of Basic and Clinical Pharmacology (NC‐IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.
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spelling pubmed-56506692017-10-26 THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Transporters Alexander, Stephen PH Kelly, Eamonn Marrion, Neil V Peters, John A Faccenda, Elena Harding, Simon D Pawson, Adam J Sharman, Joanna L Southan, Christopher Davies, Jamie A Br J Pharmacol The Concise Guide to Pharmacology 2017/18 The Concise Guide to PHARMACOLOGY 2017/18 provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide represents approximately 400 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point‐in‐time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.13883/full. Transporters are one of the eight major pharmacological targets into which the Guide is divided, with the others being: G protein‐coupled receptors, ligand‐gated ion channels, voltage‐gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors and enzymes. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid‐2017, and supersedes data presented in the 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature Committee of the Union of Basic and Clinical Pharmacology (NC‐IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate. John Wiley and Sons Inc. 2017-10-21 2017-12 /pmc/articles/PMC5650669/ /pubmed/29055035 http://dx.doi.org/10.1111/bph.13883 Text en © 2017 The Authors. British Journal of Pharmacology published by John Wiley & Sons Ltd on behalf of British Pharmacological Society. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle The Concise Guide to Pharmacology 2017/18
Alexander, Stephen PH
Kelly, Eamonn
Marrion, Neil V
Peters, John A
Faccenda, Elena
Harding, Simon D
Pawson, Adam J
Sharman, Joanna L
Southan, Christopher
Davies, Jamie A
THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Transporters
title THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Transporters
title_full THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Transporters
title_fullStr THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Transporters
title_full_unstemmed THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Transporters
title_short THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Transporters
title_sort concise guide to pharmacology 2017/18: transporters
topic The Concise Guide to Pharmacology 2017/18
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650669/
https://www.ncbi.nlm.nih.gov/pubmed/29055035
http://dx.doi.org/10.1111/bph.13883
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