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Immune Repertoire after Immunization As Seen by Next-Generation Sequencing and Proteomics

The immune system produces a diverse repertoire of immunoglobulins in response to foreign antigens. During B-cell development, VDJ recombination and somatic mutations generate diversity, whereas selection processes remove it. Using both proteomic and NGS approaches, we characterized the immune reper...

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Detalles Bibliográficos
Autores principales:	VanDuijn, Martijn M., Dekker, Lennard J., van IJcken, Wilfred F. J., Sillevis Smitt, Peter A. E., Luider, Theo M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650670/ https://www.ncbi.nlm.nih.gov/pubmed/29085363 http://dx.doi.org/10.3389/fimmu.2017.01286

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