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Is There an Opportunity for Current Chemotherapeutics to Up-regulate MIC-A/B Ligands?
Natural killer (NK) cells are critical effectors of the immune system. NK cells recognize unhealthy cells by specific ligands [e.g., MHC- class I chain related protein A or B (MIC-A/B)] for further elimination by cytotoxicity. Paradoxically, cancer cells down-regulate MIC-A/B and evade NK cell’s ant...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651020/ https://www.ncbi.nlm.nih.gov/pubmed/29089892 http://dx.doi.org/10.3389/fphar.2017.00732 |