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Selective Limbic Blood–Brain Barrier Breakdown in a Feline Model of Limbic Encephalitis with LGI1 Antibodies

Human leucine-rich glioma-inactivated protein 1 encephalitis (LGI1) is an autoimmune limbic encephalitis in which serum and cerebrospinal fluid contain antibodies targeting LGI1, a protein of the voltage gated potassium channel (VGKC) complex. Recently, we showed that a feline model of limbic enceph...

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Detalles Bibliográficos
Autores principales: Tröscher, Anna R., Klang, Andrea, French, Maria, Quemada-Garrido, Lucía, Kneissl, Sibylle Maria, Bien, Christian G., Pákozdy, Ákos, Bauer, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651237/
https://www.ncbi.nlm.nih.gov/pubmed/29093718
http://dx.doi.org/10.3389/fimmu.2017.01364