NPT088 reduces both amyloid-β and tau pathologies in transgenic mice

INTRODUCTION: Alzheimer's disease (AD) is characterized by appearance of both extracellular senile plaques and intracellular neurofibrillary tangles, comprised of aggregates of misfolded amyloid-β (Aβ) and hyper-phosphorylated tau, respectively. In a previous study, we demonstrated that g3p, a...

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Detalles Bibliográficos
Autores principales: Levenson, Jonathan M., Schroeter, Sally, Carroll, Jenna C., Cullen, Valerie, Asp, Eva, Proschitsky, Ming, Chung, Charlotte H.-Y., Gilead, Sharon, Nadeem, Muhammad, Dodiya, Hemraj B., Shoaga, Shadiyat, Mufson, Elliott J., Tsubery, Haim, Krishnan, Rajaraman, Wright, Jason, Solomon, Beka, Fisher, Richard, Gannon, Kimberley S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651359/
https://www.ncbi.nlm.nih.gov/pubmed/29067301
http://dx.doi.org/10.1016/j.trci.2016.06.004

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