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Combination treatment with leptin and pioglitazone in a mouse model of Alzheimer's disease

INTRODUCTION: Combination therapy approaches may be necessary to address the many facets of pathologic change in the brain in Alzheimer's disease (AD). The drugs leptin and pioglitazone have previously been shown individually to have neuroprotective and anti-inflammatory actions, respectively,...

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Detalles Bibliográficos
Autores principales: Fernandez-Martos, Carmen M., Atkinson, Rachel A.K., Chuah, Meng I., King, Anna E., Vickers, James C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651376/
https://www.ncbi.nlm.nih.gov/pubmed/29067321
http://dx.doi.org/10.1016/j.trci.2016.11.002