shRNA-mediated downregulation of α-N-Acetylgalactosaminidase inhibits migration and invasion of cancer cell lines

OBJECTIVE(S): Extracellular matrix (ECM) is composed of many kinds of glycoproteins containing glycosaminoglycans (GAGs) moiety. The research was conducted based on the N-Acetylgalactosamine (GalNAc) degradation of ECM components by α-N-acetylgalactosaminidase (Nagalase) which facilitates migration...

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Detalles Bibliográficos
Autores principales: Saburi, Ehsan, Tavakolafshari, Jalil, Mortazavi, Yousef, Biglari, Alireza, Mirzaei, Seyed Abbas, Nadri, Samad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651455/
https://www.ncbi.nlm.nih.gov/pubmed/29085597
http://dx.doi.org/10.22038/IJBMS.2017.9271

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