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Potential fluoride toxicity from oral medicaments: A review
The beneficial effects of fluoride on human oral health are well studied. There are numerous studies demonstrating that a small amount of fluoride delivered to the oral cavity decreases the prevalence of dental decay and results in stronger teeth and bones. However, ingestion of fluoride more than t...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mashhad University of Medical Sciences
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651468/ https://www.ncbi.nlm.nih.gov/pubmed/29085574 http://dx.doi.org/10.22038/IJBMS.2017.9104 |
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author | Ullah, Rizwan Zafar, Muhammad Sohail Shahani, Nazish |
author_facet | Ullah, Rizwan Zafar, Muhammad Sohail Shahani, Nazish |
author_sort | Ullah, Rizwan |
collection | PubMed |
description | The beneficial effects of fluoride on human oral health are well studied. There are numerous studies demonstrating that a small amount of fluoride delivered to the oral cavity decreases the prevalence of dental decay and results in stronger teeth and bones. However, ingestion of fluoride more than the recommended limit leads to toxicity and adverse effects. In order to update our understanding of fluoride and its potential toxicity, we have described the mechanisms of fluoride metabolism, toxic effects, and management of fluoride toxicity. The main aim of this review is to highlight the potential adverse effects of fluoride overdose and poorly understood toxicity. In addition, the related clinical significance of fluoride overdose and toxicity has been discussed. |
format | Online Article Text |
id | pubmed-5651468 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Mashhad University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-56514682017-10-30 Potential fluoride toxicity from oral medicaments: A review Ullah, Rizwan Zafar, Muhammad Sohail Shahani, Nazish Iran J Basic Med Sci Review Article The beneficial effects of fluoride on human oral health are well studied. There are numerous studies demonstrating that a small amount of fluoride delivered to the oral cavity decreases the prevalence of dental decay and results in stronger teeth and bones. However, ingestion of fluoride more than the recommended limit leads to toxicity and adverse effects. In order to update our understanding of fluoride and its potential toxicity, we have described the mechanisms of fluoride metabolism, toxic effects, and management of fluoride toxicity. The main aim of this review is to highlight the potential adverse effects of fluoride overdose and poorly understood toxicity. In addition, the related clinical significance of fluoride overdose and toxicity has been discussed. Mashhad University of Medical Sciences 2017-08 /pmc/articles/PMC5651468/ /pubmed/29085574 http://dx.doi.org/10.22038/IJBMS.2017.9104 Text en Copyright: © Iranian Journal of Basic Medical Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Ullah, Rizwan Zafar, Muhammad Sohail Shahani, Nazish Potential fluoride toxicity from oral medicaments: A review |
title | Potential fluoride toxicity from oral medicaments: A review |
title_full | Potential fluoride toxicity from oral medicaments: A review |
title_fullStr | Potential fluoride toxicity from oral medicaments: A review |
title_full_unstemmed | Potential fluoride toxicity from oral medicaments: A review |
title_short | Potential fluoride toxicity from oral medicaments: A review |
title_sort | potential fluoride toxicity from oral medicaments: a review |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651468/ https://www.ncbi.nlm.nih.gov/pubmed/29085574 http://dx.doi.org/10.22038/IJBMS.2017.9104 |
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