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Dihydroartemisinin Induces Apoptosis in Human Bladder Cancer Cell Lines Through Reactive Oxygen Species, Mitochondrial Membrane Potential, and Cytochrome C Pathway

BACKGROUND: Dihydroartemisinin (DHA) is a semisynthetic derivative of artemisinin and has antiproliferative effect. However, such effects of DHA have not yet been revealed for bladder cancer cells. METHODS: We used as bladder cancer cell lines to examine the effect of DHA on the cell viability, cell...

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Detalles Bibliográficos
Autores principales: Poupel, Farhad, Aghaei, Mahmoud, Movahedian, Ahmad, Jafari, Seyyed Mehdi, Shahrestanaki, Mohammad Keyvanloo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651661/
https://www.ncbi.nlm.nih.gov/pubmed/29114376
http://dx.doi.org/10.4103/ijpvm.IJPVM_258_17