Cargando…

Systematic identification of regulatory variants associated with cancer risk

BACKGROUND: Most cancer risk-associated single nucleotide polymorphisms (SNPs) identified by genome-wide association studies (GWAS) are noncoding and it is challenging to assess their functional impacts. To systematically identify the SNPs that affect gene expression by modulating activities of dist...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Song, Liu, Yuwen, Zhang, Qin, Wu, Jiayu, Liang, Junbo, Yu, Shan, Wei, Gong-Hong, White, Kevin P., Wang, Xiaoyue
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651703/ https://www.ncbi.nlm.nih.gov/pubmed/29061142 http://dx.doi.org/10.1186/s13059-017-1322-z

Ejemplares similares

Identification of pathogenic variants in cancer genes using base editing screens with editing efficiency correction
por: Huang, Changcai, et al.
Publicado: (2021)

Identification of a Potential Regulatory Variant for Colorectal Cancer Risk Mapping to 3p21.31 in Chinese Population
por: Ke, Juntao, et al.
Publicado: (2016)

Identification of a Potential Regulatory Variant for Colorectal Cancer Risk Mapping to Chromosome 5q31.1: A Post-GWAS Study
por: Ke, Juntao, et al.
Publicado: (2015)

Systematic identification of cis-regulatory variants that cause gene expression differences in a yeast cross
por: Renganaath, Kaushik, et al.
Publicado: (2020)

Identification and functional study of GATA4 gene regulatory variants in atrial septal defects
por: Fan, Dongchen, et al.
Publicado: (2021)

Identification of Biomarkers Related to Regulatory T Cell Infiltration in Oral Squamous Cell Carcinoma Based on Integrated Bioinformatics Analysis
por: Wang, Chao, et al.
Publicado: (2022)

Identification of regulatory variants associated with genetic susceptibility to meningococcal disease
por: Borghini, Lisa, et al.
Publicado: (2019)

Quantifying deleterious effects of regulatory variants
por: Li, Shan, et al.
Publicado: (2017)

Systematic characterization of regulatory variants of blood pressure genes
por: Oliveros, Winona, et al.
Publicado: (2023)

The Identification and Validation of Hub Genes Associated with Acute Myocardial Infarction Using Weighted Gene Co-Expression Network Analysis
por: Xue, Junqiang, et al.
Publicado: (2022)

Identification of transcriptional regulatory variants in pig duodenum, liver, and muscle tissues
por: Crespo-Piazuelo, Daniel, et al.
Publicado: (2023)

Mapping regulatory variants controlling gene expression in drought response and tolerance in maize
por: Liu, Shengxue, et al.
Publicado: (2020)

Genetic variants in regulatory regions of microRNAs are associated with lung cancer risk
por: Xie, Kaipeng, et al.
Publicado: (2016)

Functional genomic analysis delineates regulatory mechanisms of GWAS-identified bipolar disorder risk variants
por: Chen, Rui, et al.
Publicado: (2022)

Identification of regulatory modules in genome scale transcription regulatory networks
por: Song, Qi, et al.
Publicado: (2017)

Regulatory effect of gut microbes on blood pressure
por: Yan, Dong, et al.
Publicado: (2022)

Identification of a variant form of tyrosine phosphatase LYP
por: Wang, Shaofeng, et al.
Publicado: (2010)

Uncovering a Dynamic Feature of the Transcriptional Regulatory Network for Anterior-Posterior Patterning in the Drosophila Embryo
por: Liu, Junbo, et al.
Publicado: (2013)

Systematic identification of regulatory proteins critical for T-cell activation
por: Chu, Peter, et al.
Publicado: (2003)

Identification of MicroRNA-Target Gene-Transcription Factor Regulatory Networks in Colorectal Adenoma Using Microarray Expression Data
por: Gao, Yadong, et al.
Publicado: (2020)

Identification and regulatory network analysis of SPL family transcription factors in Populus euphratica Oliv. heteromorphic leaves
por: Qin, Shao-Wei, et al.
Publicado: (2022)

Correction: Uncovering a Dynamic Feature of the Transcriptional Regulatory Network for Anterior-Posterior Patterning in the Drosophila Embryo
por: Liu, Junbo, et al.
Publicado: (2014)

Correction: Uncovering a Dynamic Feature of the Transcriptional Regulatory Network for Anterior-Posterior Patterning in the Drosophila Embryo
por: Liu, Junbo, et al.
Publicado: (2014)

The identification of two regulatory ESCC susceptibility genetic variants in the TERT-CLPTM1L loci
por: Zhou, Liqing, et al.
Publicado: (2015)

chromMAGMA: regulatory element-centric interrogation of risk variants
por: Nameki, Robbin, et al.
Publicado: (2022)

Remotely acting SMCHD1 gene regulatory elements: in silico prediction and identification of potential regulatory variants in patients with FSHD
por: Mayes, Mary B., et al.
Publicado: (2015)

Identification of Transcription Regulatory Relationships in Diabetic Nephropathy
por: Shi, Jing-Song, et al.
Publicado: (2018)

Systematic investigation of allelic regulatory activity of schizophrenia-associated common variants
por: McAfee, Jessica C., et al.
Publicado: (2023)

Identification of circRNA-miRNA-mRNA regulatory network and its role in cardiac hypertrophy
por: Gong, Ke, et al.
Publicado: (2023)

Combining single-cell transcriptomics and CellTagging to identify differentiation trajectories of human adipose-derived mesenchymal stem cells
por: Lin, Kai, et al.
Publicado: (2023)

Germline Variants and Genetic Interactions of Several EMT Regulatory Genes Increase the Risk of HBV-Related Hepatocellular Carcinoma
por: Liu, Wen-Xuan, et al.
Publicado: (2021)

A Genetic Variant in miRNA-219-1 Is Associated with Risk of Esophageal Squamous Cell Carcinoma in Chinese Kazakhs
por: Song, Xiaoyue, et al.
Publicado: (2015)

On the identification of potential regulatory variants within genome wide association candidate SNP sets
por: Chen, Chih-yu, et al.
Publicado: (2014)

Identification of rare and common regulatory variants in pluripotent cells using population-scale transcriptomics
por: Bonder, Marc Jan, et al.
Publicado: (2021)

Identification of a functional variant for colorectal cancer risk mapping to chromosome 5q31.1
por: Ke, Juntao, et al.
Publicado: (2016)

An Overview on Identification and Regulatory Mechanisms of Long Non-coding RNAs in Fungi
por: Li, Juan, et al.
Publicado: (2021)

Functional assessment of human enhancer activities using whole-genome STARR-sequencing
por: Liu, Yuwen, et al.
Publicado: (2017)

Familial analysis reveals rare risk variants for migraine in regulatory regions
por: Techlo, Tanya Ramdal, et al.
Publicado: (2020)

Characterisation of genetic regulatory effects for osteoporosis risk variants in human osteoclasts
por: Mullin, Benjamin H., et al.
Publicado: (2020)

Identification of Runs of Homozygosity Islands and Functional Variants in Wenchang Chicken
por: Tian, Shuaishuai, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_f8go020n9cmaan2vkgf54umhu5