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Reconstruction of Toll-like receptor 9-mediated responses in HEK-Blue hTLR9 cells by transfection of human macrophage scavenger receptor 1 gene

We used human Toll-like receptor 9 (hTLR9)-expressing HEK-Blue hTLR9 cells, which release secreted embryonic alkaline phosphatase (SEAP) upon response to CpG DNA, to evaluate the immunological properties of nucleic acid drug candidates. Our preliminary studies showed that phosphodiester CpG DNA hard...

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Detalles Bibliográficos
Autores principales:	Ohtsuki, Shozo, Takahashi, Yuki, Inoue, Takao, Takakura, Yoshinobu, Nishikawa, Makiya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651873/ https://www.ncbi.nlm.nih.gov/pubmed/29057947 http://dx.doi.org/10.1038/s41598-017-13890-3

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