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Pre-fusion RSV F strongly boosts pre-fusion specific neutralizing responses in cattle pre-exposed to bovine RSV

Human respiratory syncytial virus (hRSV) is responsible for serious lower respiratory tract disease in infants and in older adults, and remains an important vaccine need. RSV fusion (F) glycoprotein is a key target for neutralizing antibodies. RSV F stabilized in its pre-fusion conformation (DS-Cav1...

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Detalles Bibliográficos
Autores principales:	Steff, Ann-Muriel, Monroe, James, Friedrich, Kristian, Chandramouli, Sumana, Nguyen, Thi Lien-Anh, Tian, Sai, Vandepaer, Sarah, Toussaint, Jean-François, Carfi, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651886/ https://www.ncbi.nlm.nih.gov/pubmed/29057917 http://dx.doi.org/10.1038/s41467-017-01092-4

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