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Exhaustive search for epistatic effects on the human methylome

Studies assessing the existence and magnitude of epistatic effects on complex human traits provide inconclusive results. The study of such effects is complicated by considerable increase in computational burden, model complexity, and model uncertainty, which in concert decrease model stability. An a...

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Detalles Bibliográficos
Autores principales: Egli, Tobias, Vukojevic, Vanja, Sengstag, Thierry, Jacquot, Martin, Cabezón, Rubén, Coynel, David, Freytag, Virginie, Heck, Angela, Vogler, Christian, de Quervain, Dominique J.-F., Papassotiropoulos, Andreas, Milnik, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651902/
https://www.ncbi.nlm.nih.gov/pubmed/29057891
http://dx.doi.org/10.1038/s41598-017-13256-9