PTP4A1 promotes TGFβ signaling and fibrosis in systemic sclerosis

Systemic sclerosis (SSc) is an autoimmune disease characterized by fibrosis of skin and internal organs. Protein tyrosine phosphatases have received little attention in the study of SSc or fibrosis. Here, we show that the tyrosine phosphatase PTP4A1 is highly expressed in fibroblasts from patients w...

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Detalles Bibliográficos
Autores principales: Sacchetti, Cristiano, Bai, Yunpeng, Stanford, Stephanie M., Di Benedetto, Paola, Cipriani, Paola, Santelli, Eugenio, Piera-Velazquez, Sonsoles, Chernitskiy, Vladimir, Kiosses, William B., Ceponis, Arnold, Kaestner, Klaus H., Boin, Francesco, Jimenez, Sergio A., Giacomelli, Roberto, Zhang, Zhong-Yin, Bottini, Nunzio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651906/
https://www.ncbi.nlm.nih.gov/pubmed/29057934
http://dx.doi.org/10.1038/s41467-017-01168-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651906/
https://www.ncbi.nlm.nih.gov/pubmed/29057934
http://dx.doi.org/10.1038/s41467-017-01168-1

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