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Non-muscular myosin light chain kinase triggers intermittent hypoxia-induced interleukin-6 release, endothelial dysfunction and permeability
Obstructive sleep apnea is characterized by intermittent hypoxia (IH) which alters endothelial function, induces inflammation and accelerates atherosclerosis-induced cardiovascular diseases. The non-muscular myosin light chain kinase (nmMLCK) isoform contributes to endothelial cell-cell junction ope...
Autores principales: | Recoquillon, Sylvain, Gómez-Guzmán, Manuel, Rodier, Marion, Koffi, Camille, Nitiéma, Mathieu, Gagnadoux, Frédéric, Martínez, M. Carmen, Andriantsitohaina, Ramaroson |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651916/ https://www.ncbi.nlm.nih.gov/pubmed/29057883 http://dx.doi.org/10.1038/s41598-017-13268-5 |
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