Cargando…

Diabetes, the TYK2 Gene and the Interferon Response: In Search for Environmental Causes

Detalles Bibliográficos
Autores principales:	Toniolo, Antonio, Leslie, Richard David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Commentary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652001/ https://www.ncbi.nlm.nih.gov/pubmed/28916157 http://dx.doi.org/10.1016/j.ebiom.2017.09.003

Ejemplares similares

The type 1 diabetes gene TYK2 regulates β-cell development and its responses to interferon-α
por: Chandra, Vikash, et al.
Publicado: (2022)

TYK2 Kinase Activity Is Required for Functional Type I Interferon Responses In Vivo
por: Prchal-Murphy, Michaela, et al.
Publicado: (2012)

TYK2 in Immune Responses and Treatment of Psoriasis
por: Shang, Lin, et al.
Publicado: (2022)

TYK2 Promoter Variant and Diabetes Mellitus in the Japanese
por: Nagafuchi, Seiho, et al.
Publicado: (2015)

TYK2 in Tumor Immunosurveillance
por: Karjalainen, Anzhelika, et al.
Publicado: (2020)

In vivo tumor surveillance by NK cells requires TYK2 but not TYK2 kinase activity
por: Prchal-Murphy, Michaela, et al.
Publicado: (2015)

Two common disease-associated TYK2 variants impact exon splicing and TYK2 dosage
por: Li, Zhi, et al.
Publicado: (2020)

Transcriptome analysis reveals a major impact of JAK protein tyrosine kinase 2 (Tyk2) on the expression of interferon-responsive and metabolic genes
por: Vogl, Claus, et al.
Publicado: (2010)

A TYK2 Gene Mutation c.2395G>A Leads to TYK2 Deficiency: A Case Report and Literature Review
por: Wu, Peilin, et al.
Publicado: (2020)

The rs2304256 Polymorphism in TYK2 Gene Is Associated with Protection for Type 1 Diabetes Mellitus
por: Pellenz, Felipe Mateus, et al.
Publicado: (2021)

TYK2: An Upstream Kinase of STATs in Cancer
por: Wöss, Katharina, et al.
Publicado: (2019)

Reduced expression of Jak-1 and Tyk-2 proteins leads to interferon resistance in Hepatitis C virus replicon
por: Hazari, Sidhartha, et al.
Publicado: (2007)

Whence Interferon? Variety in the Production of Interferon in Response to Viral Infection
por: Levy, David E.
Publicado: (2002)

Oncogenic TYK2 P760L kinase is effectively targeted by combinatorial TYK2, mTOR and CDK4/6 kinase blockade
por: Woess, Katharina, et al.
Publicado: (2022)

TYK2 Variants in B-Acute Lymphoblastic Leukaemia
por: Turrubiartes-Martínez, Edgar, et al.
Publicado: (2020)

TYK2 in Cancer Metastases: Genomic and Proteomic Discovery
por: Borcherding, Dana C., et al.
Publicado: (2021)

Tyk2 is a tumor suppressor in colorectal cancer
por: Moritsch, Stefan, et al.
Publicado: (2022)

Tyk2 Targeting in Immune-Mediated Inflammatory Diseases
por: Rusiñol, Lluís, et al.
Publicado: (2023)

The Challenging Search for Diabetic Nephropathy Genes
por: Bowden, Donald W., et al.
Publicado: (2012)

Structural basis of IFNα receptor recognition by TYK2
por: Wallweber, Heidi J.A., et al.
Publicado: (2014)

Functional characterization of NPM1–TYK2 fusion oncogene
por: Kuravi, Sudhakiranmayi, et al.
Publicado: (2022)

Single Nucleotide Polymorphism of TYK2 Gene and Susceptibility to Rheumatoid Arthritis in Iranian Population
por: Mohamadhosseini, Azadeh, et al.
Publicado: (2019)

Comprehensive analysis of three TYK2 gene variants in the susceptibility to Chagas disease infection and cardiomyopathy
por: Leon Rodriguez, Daniel A., et al.
Publicado: (2018)

Reduced Tyk2 gene expression in β-cells due to natural mutation determines susceptibility to virus-induced diabetes
por: Izumi, Kenichi, et al.
Publicado: (2015)

Direct and biologically significant interactions of human herpesvirus 8 interferon regulatory factor 1 with STAT3 and Janus kinase TYK2
por: Yang, Zunlin, et al.
Publicado: (2023)

Triple-action inhibitory mechanism of allosteric TYK2-specific inhibitors
por: Wang, Jimin, et al.
Publicado: (2023)

SIAH2 antagonizes TYK2-STAT3 signaling in lung carcinoma cells
por: Müller, Sylvia, et al.
Publicado: (2014)

Causes of early-onset type 1 diabetes: toward data-driven environmental approaches
por: Bougnères, Pierre, et al.
Publicado: (2008)

Association of germline TYK2 variation with lung cancer and non‐Hodgkin lymphoma risk
por: Yarmolinsky, James, et al.
Publicado: (2022)

Polymorphisms in IRF5 and TYK2 Genes Are Associated with Rheumatoid Arthritis in a Chinese Han Population
por: Peng, Yuqin, et al.
Publicado: (2021)

Role of Tyk-2 in Th9 and Th17 cells in allergic asthma
por: Übel, Caroline, et al.
Publicado: (2014)

Compound heterozygous TYK2 mutations underlie primary immunodeficiency with T-cell lymphopenia
por: Nemoto, Michiko, et al.
Publicado: (2018)

Expression analysis of IFNAR1 and TYK2 transcripts in COVID-19 patients
por: Akbari, Mohammadarian, et al.
Publicado: (2022)

TYK2 single-nucleotide variants associated with the severity of COVID-19 disease
por: Zabihi Rizi, Fateme, et al.
Publicado: (2023)

Prognostic values and clinical relationship of TYK2 in laryngeal squamous cell cancer
por: Fang, Lucheng, et al.
Publicado: (2021)

TYK2-induced phosphorylation of Y640 suppresses STAT3 transcriptional activity
por: Mori, Raffaele, et al.
Publicado: (2017)

Use of TYK2 inhibitor to relieve reactive granulomatous dermatitis due to myelodysplastic syndrome
por: Huang, Christina, et al.
Publicado: (2023)

TYK2 Promoter Variant Is Associated with Impaired Insulin Secretion and Lower Insulin Resistance in Japanese Type 2 Diabetes Patients
por: Mori, Hitoe, et al.
Publicado: (2021)

Dependency on the TYK2/STAT1/MCL1 axis in anaplastic large cell lymphoma
por: Prutsch, Nicole, et al.
Publicado: (2018)

Reevaluating the Impact of Epstein-Barr Virus Noncoding RNAs on the Interferon Response
por: Murphy, Eain A.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_pttvl1675nnrrjt2e1qcsj0eca