Transcriptome Analysis Uncovers a Growth-Promoting Activity of Orosomucoid-1 on Hepatocytes

The acute phase protein orosomucoid-1 (Orm1) is mainly expressed by hepatocytes (HPCs) under stress conditions. However, its specific function is not fully understood. Here, we report a role of Orm1 as an executer of HPC proliferation. Increases in serum levels of Orm1 were observed in patients afte...

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Detalles Bibliográficos
Autores principales: Qin, Xian-Yang, Hara, Mitsuko, Arner, Erik, Kawaguchi, Yoshikuni, Inoue, Ikuyo, Tatsukawa, Hideki, Furutani, Yutaka, Nagatsuma, Keisuke, Matsuura, Tomokazu, Wei, Feifei, Kikuchi, Jun, Sone, Hideko, Daub, Carsten, Kawaji, Hideya, Lassmann, Timo, Itoh, Masayoshi, Suzuki, Harukazu, Carninci, Piero, Hayashizaki, Yoshihide, Kokudo, Norihiro, Forrest, Alistair R.R., Kojima, Soichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652006/
https://www.ncbi.nlm.nih.gov/pubmed/28927749
http://dx.doi.org/10.1016/j.ebiom.2017.09.008

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