FledFold: A Novel Software for RNA Secondary Structure Prediction

BACKGROUND: RNA secondary structure is essential to understand the mechanism of RNAs. METHOD: In this paper, fledFold, a novel software for RNA secondary structure prediction, is introduced. It combines both thermodynamic and kinetic factors of RNA secondary structures and can predict RNA secondary...

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Detalles Bibliográficos
Autores principales: Zhao, Qi, Liu, Yuanning, Duan, Yunna, Dai, Tao, Xu, Rui, Guo, Hao, Fan, Daiming, Nie, Yongzhan, Zhang, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652076/
https://www.ncbi.nlm.nih.gov/pubmed/29123460
http://dx.doi.org/10.2174/1570178614666170419122621
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author Zhao, Qi
Liu, Yuanning
Duan, Yunna
Dai, Tao
Xu, Rui
Guo, Hao
Fan, Daiming
Nie, Yongzhan
Zhang, Hao
author_facet Zhao, Qi
Liu, Yuanning
Duan, Yunna
Dai, Tao
Xu, Rui
Guo, Hao
Fan, Daiming
Nie, Yongzhan
Zhang, Hao
author_sort Zhao, Qi
collection PubMed
description BACKGROUND: RNA secondary structure is essential to understand the mechanism of RNAs. METHOD: In this paper, fledFold, a novel software for RNA secondary structure prediction, is introduced. It combines both thermodynamic and kinetic factors of RNA secondary structures and can predict RNA secondary structures from their primary sequences with local personal computers. RESULTS: FledFold is implemented in C++ under Windows 7 and could run on windows 7 or later version with at least 2 GB of RAM. Fledfold is user friendly and could output results with multiple formats. CONSLUSION: FledFold will be a valuable tool for RNA researches and it could be downloaded freely from http://www.jlucomputer.com/fledfold.php
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spelling pubmed-56520762017-11-07 FledFold: A Novel Software for RNA Secondary Structure Prediction Zhao, Qi Liu, Yuanning Duan, Yunna Dai, Tao Xu, Rui Guo, Hao Fan, Daiming Nie, Yongzhan Zhang, Hao Lett Org Chem Article BACKGROUND: RNA secondary structure is essential to understand the mechanism of RNAs. METHOD: In this paper, fledFold, a novel software for RNA secondary structure prediction, is introduced. It combines both thermodynamic and kinetic factors of RNA secondary structures and can predict RNA secondary structures from their primary sequences with local personal computers. RESULTS: FledFold is implemented in C++ under Windows 7 and could run on windows 7 or later version with at least 2 GB of RAM. Fledfold is user friendly and could output results with multiple formats. CONSLUSION: FledFold will be a valuable tool for RNA researches and it could be downloaded freely from http://www.jlucomputer.com/fledfold.php Bentham Science Publishers 2017-06 2017-06 /pmc/articles/PMC5652076/ /pubmed/29123460 http://dx.doi.org/10.2174/1570178614666170419122621 Text en © 2017 Bentham Science Publishers https://creativecommons.org/licenses/by-nc/4.0/legalcode This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/legalcode), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
spellingShingle Article
Zhao, Qi
Liu, Yuanning
Duan, Yunna
Dai, Tao
Xu, Rui
Guo, Hao
Fan, Daiming
Nie, Yongzhan
Zhang, Hao
FledFold: A Novel Software for RNA Secondary Structure Prediction
title FledFold: A Novel Software for RNA Secondary Structure Prediction
title_full FledFold: A Novel Software for RNA Secondary Structure Prediction
title_fullStr FledFold: A Novel Software for RNA Secondary Structure Prediction
title_full_unstemmed FledFold: A Novel Software for RNA Secondary Structure Prediction
title_short FledFold: A Novel Software for RNA Secondary Structure Prediction
title_sort fledfold: a novel software for rna secondary structure prediction
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652076/
https://www.ncbi.nlm.nih.gov/pubmed/29123460
http://dx.doi.org/10.2174/1570178614666170419122621
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