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HR+, HER2– Advanced Breast Cancer and CDK4/6 Inhibitors: Mode of Action, Clinical Activity, and Safety Profiles

BACKGROUND: Cyclin-dependent kinase (CDK) 4/6 inhibitor-based therapies have shown great promise in improving clinical outcomes for patients with hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2–) advanced breast cancer. OBJECTIVES: 1. Discuss the mode of acti...

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Detalles Bibliográficos
Autores principales:	Sammons, Sarah L., Topping, Donna L., Blackwell, Kimberly L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652078/ https://www.ncbi.nlm.nih.gov/pubmed/28359238 http://dx.doi.org/10.2174/1568009617666170330120452

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