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Concurrent Multilevel Spinal Intra-medullary with Extensive Intracranial Tuberculomas: A Rare Case Report

Disseminated tuberculomas in the brain and spinal cord are rare. To the best of our knowledge, only nine cases of spinal intra-medullary tuberculomas with cranial involvement have been reported till date. However, involvement of all levels in the spinal cord, brain stem with pan lobar involvement of...

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Autores principales: Krishnan, Shyam Sundar, Patel, Bhavinkumar Rameshchandra, Vasudevan, Madabushi Chakravarthy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652122/
https://www.ncbi.nlm.nih.gov/pubmed/29114310
http://dx.doi.org/10.4103/1793-5482.185073
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author Krishnan, Shyam Sundar
Patel, Bhavinkumar Rameshchandra
Vasudevan, Madabushi Chakravarthy
author_facet Krishnan, Shyam Sundar
Patel, Bhavinkumar Rameshchandra
Vasudevan, Madabushi Chakravarthy
author_sort Krishnan, Shyam Sundar
collection PubMed
description Disseminated tuberculomas in the brain and spinal cord are rare. To the best of our knowledge, only nine cases of spinal intra-medullary tuberculomas with cranial involvement have been reported till date. However, involvement of all levels in the spinal cord, brain stem with pan lobar involvement of the cerebrum and cerebellum has not been reported so far. We present such a case of a 12-year-old boy with history of pulmonary tuberculosis, who presented with gradual onset of quadriparesis and generalized seizures. We have discussed the unusual clinical presentation and the temporal changes in magnetic resonance imaging features along with clinical response to treatment. In cases reported so far, the plan of surgical versus medical management has been opted for variably, in cases of spinal intra-medullary involvement with acute neurological deficit. The decision is even more difficult in multilevel spinal intra-medullary tuberculomas. Our patient showed good clinico-radiological improvement with medical management.
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spelling pubmed-56521222017-11-07 Concurrent Multilevel Spinal Intra-medullary with Extensive Intracranial Tuberculomas: A Rare Case Report Krishnan, Shyam Sundar Patel, Bhavinkumar Rameshchandra Vasudevan, Madabushi Chakravarthy Asian J Neurosurg Case Report Disseminated tuberculomas in the brain and spinal cord are rare. To the best of our knowledge, only nine cases of spinal intra-medullary tuberculomas with cranial involvement have been reported till date. However, involvement of all levels in the spinal cord, brain stem with pan lobar involvement of the cerebrum and cerebellum has not been reported so far. We present such a case of a 12-year-old boy with history of pulmonary tuberculosis, who presented with gradual onset of quadriparesis and generalized seizures. We have discussed the unusual clinical presentation and the temporal changes in magnetic resonance imaging features along with clinical response to treatment. In cases reported so far, the plan of surgical versus medical management has been opted for variably, in cases of spinal intra-medullary involvement with acute neurological deficit. The decision is even more difficult in multilevel spinal intra-medullary tuberculomas. Our patient showed good clinico-radiological improvement with medical management. Medknow Publications & Media Pvt Ltd 2017 /pmc/articles/PMC5652122/ /pubmed/29114310 http://dx.doi.org/10.4103/1793-5482.185073 Text en Copyright: © 2016 Asian Journal of Neurosurgery http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Krishnan, Shyam Sundar
Patel, Bhavinkumar Rameshchandra
Vasudevan, Madabushi Chakravarthy
Concurrent Multilevel Spinal Intra-medullary with Extensive Intracranial Tuberculomas: A Rare Case Report
title Concurrent Multilevel Spinal Intra-medullary with Extensive Intracranial Tuberculomas: A Rare Case Report
title_full Concurrent Multilevel Spinal Intra-medullary with Extensive Intracranial Tuberculomas: A Rare Case Report
title_fullStr Concurrent Multilevel Spinal Intra-medullary with Extensive Intracranial Tuberculomas: A Rare Case Report
title_full_unstemmed Concurrent Multilevel Spinal Intra-medullary with Extensive Intracranial Tuberculomas: A Rare Case Report
title_short Concurrent Multilevel Spinal Intra-medullary with Extensive Intracranial Tuberculomas: A Rare Case Report
title_sort concurrent multilevel spinal intra-medullary with extensive intracranial tuberculomas: a rare case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652122/
https://www.ncbi.nlm.nih.gov/pubmed/29114310
http://dx.doi.org/10.4103/1793-5482.185073
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AT vasudevanmadabushichakravarthy concurrentmultilevelspinalintramedullarywithextensiveintracranialtuberculomasararecasereport