Zika Virus Persistence and Higher Viral Loads in Cutaneous Capillaries Than in Venous Blood

We collected venous and capillary serum samples from 21 Zika virus‒infected patients on multiple days after symptom onset and found RNA load was higher and median duration of virus detection significantly longer in capillary than in venous blood. These findings raise questions about the role of the...

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Autores principales: Matheus, Séverine, de Laval, Franck, Moua, David, N’Guyen, Christophe, Martinez, Enguerrane, Rousset, Dominique, Briolant, Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2017
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652410/
https://www.ncbi.nlm.nih.gov/pubmed/28930015
http://dx.doi.org/10.3201/eid2311.170337
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author Matheus, Séverine
de Laval, Franck
Moua, David
N’Guyen, Christophe
Martinez, Enguerrane
Rousset, Dominique
Briolant, Sébastien
author_facet Matheus, Séverine
de Laval, Franck
Moua, David
N’Guyen, Christophe
Martinez, Enguerrane
Rousset, Dominique
Briolant, Sébastien
author_sort Matheus, Séverine
collection PubMed
description We collected venous and capillary serum samples from 21 Zika virus‒infected patients on multiple days after symptom onset and found RNA load was higher and median duration of virus detection significantly longer in capillary than in venous blood. These findings raise questions about the role of the capillary compartment in virus transmission dynamics.
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spelling pubmed-56524102017-11-01 Zika Virus Persistence and Higher Viral Loads in Cutaneous Capillaries Than in Venous Blood Matheus, Séverine de Laval, Franck Moua, David N’Guyen, Christophe Martinez, Enguerrane Rousset, Dominique Briolant, Sébastien Emerg Infect Dis Research Letter We collected venous and capillary serum samples from 21 Zika virus‒infected patients on multiple days after symptom onset and found RNA load was higher and median duration of virus detection significantly longer in capillary than in venous blood. These findings raise questions about the role of the capillary compartment in virus transmission dynamics. Centers for Disease Control and Prevention 2017-11 /pmc/articles/PMC5652410/ /pubmed/28930015 http://dx.doi.org/10.3201/eid2311.170337 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research Letter
Matheus, Séverine
de Laval, Franck
Moua, David
N’Guyen, Christophe
Martinez, Enguerrane
Rousset, Dominique
Briolant, Sébastien
Zika Virus Persistence and Higher Viral Loads in Cutaneous Capillaries Than in Venous Blood
title Zika Virus Persistence and Higher Viral Loads in Cutaneous Capillaries Than in Venous Blood
title_full Zika Virus Persistence and Higher Viral Loads in Cutaneous Capillaries Than in Venous Blood
title_fullStr Zika Virus Persistence and Higher Viral Loads in Cutaneous Capillaries Than in Venous Blood
title_full_unstemmed Zika Virus Persistence and Higher Viral Loads in Cutaneous Capillaries Than in Venous Blood
title_short Zika Virus Persistence and Higher Viral Loads in Cutaneous Capillaries Than in Venous Blood
title_sort zika virus persistence and higher viral loads in cutaneous capillaries than in venous blood
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652410/
https://www.ncbi.nlm.nih.gov/pubmed/28930015
http://dx.doi.org/10.3201/eid2311.170337
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