Legionnaires’ Disease Outbreak Caused by Endemic Strain of Legionella pneumophila, New York, New York, USA, 2015

During the summer of 2015, New York, New York, USA, had one of the largest and deadliest outbreaks of Legionnaires’ disease in the history of the United States. A total of 138 cases and 16 deaths were linked to a single cooling tower in the South Bronx. Analysis of environmental samples and clinical...

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Autores principales: Lapierre, Pascal, Nazarian, Elizabeth, Zhu, Yan, Wroblewski, Danielle, Saylors, Amy, Passaretti, Teresa, Hughes, Scott, Tran, Anthony, Lin, Ying, Kornblum, John, Morrison, Shatavia S., Mercante, Jeffrey W., Fitzhenry, Robert, Weiss, Don, Raphael, Brian H., Varma, Jay K., Zucker, Howard A., Rakeman, Jennifer L., Musser, Kimberlee A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652421/
https://www.ncbi.nlm.nih.gov/pubmed/29047425
http://dx.doi.org/10.3201/eid2311.170308
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author Lapierre, Pascal
Nazarian, Elizabeth
Zhu, Yan
Wroblewski, Danielle
Saylors, Amy
Passaretti, Teresa
Hughes, Scott
Tran, Anthony
Lin, Ying
Kornblum, John
Morrison, Shatavia S.
Mercante, Jeffrey W.
Fitzhenry, Robert
Weiss, Don
Raphael, Brian H.
Varma, Jay K.
Zucker, Howard A.
Rakeman, Jennifer L.
Musser, Kimberlee A.
author_facet Lapierre, Pascal
Nazarian, Elizabeth
Zhu, Yan
Wroblewski, Danielle
Saylors, Amy
Passaretti, Teresa
Hughes, Scott
Tran, Anthony
Lin, Ying
Kornblum, John
Morrison, Shatavia S.
Mercante, Jeffrey W.
Fitzhenry, Robert
Weiss, Don
Raphael, Brian H.
Varma, Jay K.
Zucker, Howard A.
Rakeman, Jennifer L.
Musser, Kimberlee A.
author_sort Lapierre, Pascal
collection PubMed
description During the summer of 2015, New York, New York, USA, had one of the largest and deadliest outbreaks of Legionnaires’ disease in the history of the United States. A total of 138 cases and 16 deaths were linked to a single cooling tower in the South Bronx. Analysis of environmental samples and clinical isolates showed that sporadic cases of legionellosis before, during, and after the outbreak could be traced to a slowly evolving, single-ancestor strain. Detection of an ostensibly virulent Legionella strain endemic to the Bronx community suggests potential risk for future cases of legionellosis in the area. The genetic homogeneity of the Legionella population in this area might complicate investigations and interpretations of future outbreaks of Legionnaires’ disease.
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spelling pubmed-56524212017-11-01 Legionnaires’ Disease Outbreak Caused by Endemic Strain of Legionella pneumophila, New York, New York, USA, 2015 Lapierre, Pascal Nazarian, Elizabeth Zhu, Yan Wroblewski, Danielle Saylors, Amy Passaretti, Teresa Hughes, Scott Tran, Anthony Lin, Ying Kornblum, John Morrison, Shatavia S. Mercante, Jeffrey W. Fitzhenry, Robert Weiss, Don Raphael, Brian H. Varma, Jay K. Zucker, Howard A. Rakeman, Jennifer L. Musser, Kimberlee A. Emerg Infect Dis Research During the summer of 2015, New York, New York, USA, had one of the largest and deadliest outbreaks of Legionnaires’ disease in the history of the United States. A total of 138 cases and 16 deaths were linked to a single cooling tower in the South Bronx. Analysis of environmental samples and clinical isolates showed that sporadic cases of legionellosis before, during, and after the outbreak could be traced to a slowly evolving, single-ancestor strain. Detection of an ostensibly virulent Legionella strain endemic to the Bronx community suggests potential risk for future cases of legionellosis in the area. The genetic homogeneity of the Legionella population in this area might complicate investigations and interpretations of future outbreaks of Legionnaires’ disease. Centers for Disease Control and Prevention 2017-11 /pmc/articles/PMC5652421/ /pubmed/29047425 http://dx.doi.org/10.3201/eid2311.170308 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research
Lapierre, Pascal
Nazarian, Elizabeth
Zhu, Yan
Wroblewski, Danielle
Saylors, Amy
Passaretti, Teresa
Hughes, Scott
Tran, Anthony
Lin, Ying
Kornblum, John
Morrison, Shatavia S.
Mercante, Jeffrey W.
Fitzhenry, Robert
Weiss, Don
Raphael, Brian H.
Varma, Jay K.
Zucker, Howard A.
Rakeman, Jennifer L.
Musser, Kimberlee A.
Legionnaires’ Disease Outbreak Caused by Endemic Strain of Legionella pneumophila, New York, New York, USA, 2015
title Legionnaires’ Disease Outbreak Caused by Endemic Strain of Legionella pneumophila, New York, New York, USA, 2015
title_full Legionnaires’ Disease Outbreak Caused by Endemic Strain of Legionella pneumophila, New York, New York, USA, 2015
title_fullStr Legionnaires’ Disease Outbreak Caused by Endemic Strain of Legionella pneumophila, New York, New York, USA, 2015
title_full_unstemmed Legionnaires’ Disease Outbreak Caused by Endemic Strain of Legionella pneumophila, New York, New York, USA, 2015
title_short Legionnaires’ Disease Outbreak Caused by Endemic Strain of Legionella pneumophila, New York, New York, USA, 2015
title_sort legionnaires’ disease outbreak caused by endemic strain of legionella pneumophila, new york, new york, usa, 2015
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652421/
https://www.ncbi.nlm.nih.gov/pubmed/29047425
http://dx.doi.org/10.3201/eid2311.170308
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