Legionnaires’ Disease Outbreak Caused by Endemic Strain of Legionella pneumophila, New York, New York, USA, 2015
During the summer of 2015, New York, New York, USA, had one of the largest and deadliest outbreaks of Legionnaires’ disease in the history of the United States. A total of 138 cases and 16 deaths were linked to a single cooling tower in the South Bronx. Analysis of environmental samples and clinical...
Autores principales: | , , , , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Centers for Disease Control and Prevention
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652421/ https://www.ncbi.nlm.nih.gov/pubmed/29047425 http://dx.doi.org/10.3201/eid2311.170308 |
_version_ | 1783273053685284864 |
---|---|
author | Lapierre, Pascal Nazarian, Elizabeth Zhu, Yan Wroblewski, Danielle Saylors, Amy Passaretti, Teresa Hughes, Scott Tran, Anthony Lin, Ying Kornblum, John Morrison, Shatavia S. Mercante, Jeffrey W. Fitzhenry, Robert Weiss, Don Raphael, Brian H. Varma, Jay K. Zucker, Howard A. Rakeman, Jennifer L. Musser, Kimberlee A. |
author_facet | Lapierre, Pascal Nazarian, Elizabeth Zhu, Yan Wroblewski, Danielle Saylors, Amy Passaretti, Teresa Hughes, Scott Tran, Anthony Lin, Ying Kornblum, John Morrison, Shatavia S. Mercante, Jeffrey W. Fitzhenry, Robert Weiss, Don Raphael, Brian H. Varma, Jay K. Zucker, Howard A. Rakeman, Jennifer L. Musser, Kimberlee A. |
author_sort | Lapierre, Pascal |
collection | PubMed |
description | During the summer of 2015, New York, New York, USA, had one of the largest and deadliest outbreaks of Legionnaires’ disease in the history of the United States. A total of 138 cases and 16 deaths were linked to a single cooling tower in the South Bronx. Analysis of environmental samples and clinical isolates showed that sporadic cases of legionellosis before, during, and after the outbreak could be traced to a slowly evolving, single-ancestor strain. Detection of an ostensibly virulent Legionella strain endemic to the Bronx community suggests potential risk for future cases of legionellosis in the area. The genetic homogeneity of the Legionella population in this area might complicate investigations and interpretations of future outbreaks of Legionnaires’ disease. |
format | Online Article Text |
id | pubmed-5652421 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Centers for Disease Control and Prevention |
record_format | MEDLINE/PubMed |
spelling | pubmed-56524212017-11-01 Legionnaires’ Disease Outbreak Caused by Endemic Strain of Legionella pneumophila, New York, New York, USA, 2015 Lapierre, Pascal Nazarian, Elizabeth Zhu, Yan Wroblewski, Danielle Saylors, Amy Passaretti, Teresa Hughes, Scott Tran, Anthony Lin, Ying Kornblum, John Morrison, Shatavia S. Mercante, Jeffrey W. Fitzhenry, Robert Weiss, Don Raphael, Brian H. Varma, Jay K. Zucker, Howard A. Rakeman, Jennifer L. Musser, Kimberlee A. Emerg Infect Dis Research During the summer of 2015, New York, New York, USA, had one of the largest and deadliest outbreaks of Legionnaires’ disease in the history of the United States. A total of 138 cases and 16 deaths were linked to a single cooling tower in the South Bronx. Analysis of environmental samples and clinical isolates showed that sporadic cases of legionellosis before, during, and after the outbreak could be traced to a slowly evolving, single-ancestor strain. Detection of an ostensibly virulent Legionella strain endemic to the Bronx community suggests potential risk for future cases of legionellosis in the area. The genetic homogeneity of the Legionella population in this area might complicate investigations and interpretations of future outbreaks of Legionnaires’ disease. Centers for Disease Control and Prevention 2017-11 /pmc/articles/PMC5652421/ /pubmed/29047425 http://dx.doi.org/10.3201/eid2311.170308 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited. |
spellingShingle | Research Lapierre, Pascal Nazarian, Elizabeth Zhu, Yan Wroblewski, Danielle Saylors, Amy Passaretti, Teresa Hughes, Scott Tran, Anthony Lin, Ying Kornblum, John Morrison, Shatavia S. Mercante, Jeffrey W. Fitzhenry, Robert Weiss, Don Raphael, Brian H. Varma, Jay K. Zucker, Howard A. Rakeman, Jennifer L. Musser, Kimberlee A. Legionnaires’ Disease Outbreak Caused by Endemic Strain of Legionella pneumophila, New York, New York, USA, 2015 |
title | Legionnaires’ Disease Outbreak Caused by Endemic Strain of Legionella pneumophila, New York, New York, USA, 2015 |
title_full | Legionnaires’ Disease Outbreak Caused by Endemic Strain of Legionella pneumophila, New York, New York, USA, 2015 |
title_fullStr | Legionnaires’ Disease Outbreak Caused by Endemic Strain of Legionella pneumophila, New York, New York, USA, 2015 |
title_full_unstemmed | Legionnaires’ Disease Outbreak Caused by Endemic Strain of Legionella pneumophila, New York, New York, USA, 2015 |
title_short | Legionnaires’ Disease Outbreak Caused by Endemic Strain of Legionella pneumophila, New York, New York, USA, 2015 |
title_sort | legionnaires’ disease outbreak caused by endemic strain of legionella pneumophila, new york, new york, usa, 2015 |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652421/ https://www.ncbi.nlm.nih.gov/pubmed/29047425 http://dx.doi.org/10.3201/eid2311.170308 |
work_keys_str_mv | AT lapierrepascal legionnairesdiseaseoutbreakcausedbyendemicstrainoflegionellapneumophilanewyorknewyorkusa2015 AT nazarianelizabeth legionnairesdiseaseoutbreakcausedbyendemicstrainoflegionellapneumophilanewyorknewyorkusa2015 AT zhuyan legionnairesdiseaseoutbreakcausedbyendemicstrainoflegionellapneumophilanewyorknewyorkusa2015 AT wroblewskidanielle legionnairesdiseaseoutbreakcausedbyendemicstrainoflegionellapneumophilanewyorknewyorkusa2015 AT saylorsamy legionnairesdiseaseoutbreakcausedbyendemicstrainoflegionellapneumophilanewyorknewyorkusa2015 AT passarettiteresa legionnairesdiseaseoutbreakcausedbyendemicstrainoflegionellapneumophilanewyorknewyorkusa2015 AT hughesscott legionnairesdiseaseoutbreakcausedbyendemicstrainoflegionellapneumophilanewyorknewyorkusa2015 AT trananthony legionnairesdiseaseoutbreakcausedbyendemicstrainoflegionellapneumophilanewyorknewyorkusa2015 AT linying legionnairesdiseaseoutbreakcausedbyendemicstrainoflegionellapneumophilanewyorknewyorkusa2015 AT kornblumjohn legionnairesdiseaseoutbreakcausedbyendemicstrainoflegionellapneumophilanewyorknewyorkusa2015 AT morrisonshatavias legionnairesdiseaseoutbreakcausedbyendemicstrainoflegionellapneumophilanewyorknewyorkusa2015 AT mercantejeffreyw legionnairesdiseaseoutbreakcausedbyendemicstrainoflegionellapneumophilanewyorknewyorkusa2015 AT fitzhenryrobert legionnairesdiseaseoutbreakcausedbyendemicstrainoflegionellapneumophilanewyorknewyorkusa2015 AT weissdon legionnairesdiseaseoutbreakcausedbyendemicstrainoflegionellapneumophilanewyorknewyorkusa2015 AT raphaelbrianh legionnairesdiseaseoutbreakcausedbyendemicstrainoflegionellapneumophilanewyorknewyorkusa2015 AT varmajayk legionnairesdiseaseoutbreakcausedbyendemicstrainoflegionellapneumophilanewyorknewyorkusa2015 AT zuckerhowarda legionnairesdiseaseoutbreakcausedbyendemicstrainoflegionellapneumophilanewyorknewyorkusa2015 AT rakemanjenniferl legionnairesdiseaseoutbreakcausedbyendemicstrainoflegionellapneumophilanewyorknewyorkusa2015 AT musserkimberleea legionnairesdiseaseoutbreakcausedbyendemicstrainoflegionellapneumophilanewyorknewyorkusa2015 |