Polyclonal Pulmonary Tuberculosis Infections and Risk for Multidrug Resistance, Lima, Peru

Because within-host Mycobacterium tuberculosis diversity complicates diagnosis and treatment of tuberculosis (TB), we measured diversity prevalence and associated factors among 3,098 pulmonary TB patients in Lima, Peru. The 161 patients with polyclonal infection were more likely than the 115 with cl...

Descripción completa

Detalles Bibliográficos
Autores principales: Nathavitharana, Ruvandhi R., Shi, Cynthia X., Chindelevitch, Leonid, Calderon, Roger, Zhang, Zibiao, Galea, Jerome T., Contreras, Carmen, Yataco, Rosa, Lecca, Leonid, Becerra, Mercedes C., Murray, Megan B., Cohen, Ted
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2017
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652442/
https://www.ncbi.nlm.nih.gov/pubmed/29048297
http://dx.doi.org/10.3201/eid2311.170077
_version_ 1783273058661826560
author Nathavitharana, Ruvandhi R.
Shi, Cynthia X.
Chindelevitch, Leonid
Calderon, Roger
Zhang, Zibiao
Galea, Jerome T.
Contreras, Carmen
Yataco, Rosa
Lecca, Leonid
Becerra, Mercedes C.
Murray, Megan B.
Cohen, Ted
author_facet Nathavitharana, Ruvandhi R.
Shi, Cynthia X.
Chindelevitch, Leonid
Calderon, Roger
Zhang, Zibiao
Galea, Jerome T.
Contreras, Carmen
Yataco, Rosa
Lecca, Leonid
Becerra, Mercedes C.
Murray, Megan B.
Cohen, Ted
author_sort Nathavitharana, Ruvandhi R.
collection PubMed
description Because within-host Mycobacterium tuberculosis diversity complicates diagnosis and treatment of tuberculosis (TB), we measured diversity prevalence and associated factors among 3,098 pulmonary TB patients in Lima, Peru. The 161 patients with polyclonal infection were more likely than the 115 with clonal or the 2,822 with simple infections to have multidrug-resistant TB.
format Online
Article
Text
id pubmed-5652442
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Centers for Disease Control and Prevention
record_format MEDLINE/PubMed
spelling pubmed-56524422017-11-01 Polyclonal Pulmonary Tuberculosis Infections and Risk for Multidrug Resistance, Lima, Peru Nathavitharana, Ruvandhi R. Shi, Cynthia X. Chindelevitch, Leonid Calderon, Roger Zhang, Zibiao Galea, Jerome T. Contreras, Carmen Yataco, Rosa Lecca, Leonid Becerra, Mercedes C. Murray, Megan B. Cohen, Ted Emerg Infect Dis Dispatch Because within-host Mycobacterium tuberculosis diversity complicates diagnosis and treatment of tuberculosis (TB), we measured diversity prevalence and associated factors among 3,098 pulmonary TB patients in Lima, Peru. The 161 patients with polyclonal infection were more likely than the 115 with clonal or the 2,822 with simple infections to have multidrug-resistant TB. Centers for Disease Control and Prevention 2017-11 /pmc/articles/PMC5652442/ /pubmed/29048297 http://dx.doi.org/10.3201/eid2311.170077 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Nathavitharana, Ruvandhi R.
Shi, Cynthia X.
Chindelevitch, Leonid
Calderon, Roger
Zhang, Zibiao
Galea, Jerome T.
Contreras, Carmen
Yataco, Rosa
Lecca, Leonid
Becerra, Mercedes C.
Murray, Megan B.
Cohen, Ted
Polyclonal Pulmonary Tuberculosis Infections and Risk for Multidrug Resistance, Lima, Peru
title Polyclonal Pulmonary Tuberculosis Infections and Risk for Multidrug Resistance, Lima, Peru
title_full Polyclonal Pulmonary Tuberculosis Infections and Risk for Multidrug Resistance, Lima, Peru
title_fullStr Polyclonal Pulmonary Tuberculosis Infections and Risk for Multidrug Resistance, Lima, Peru
title_full_unstemmed Polyclonal Pulmonary Tuberculosis Infections and Risk for Multidrug Resistance, Lima, Peru
title_short Polyclonal Pulmonary Tuberculosis Infections and Risk for Multidrug Resistance, Lima, Peru
title_sort polyclonal pulmonary tuberculosis infections and risk for multidrug resistance, lima, peru
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652442/
https://www.ncbi.nlm.nih.gov/pubmed/29048297
http://dx.doi.org/10.3201/eid2311.170077
work_keys_str_mv AT nathavitharanaruvandhir polyclonalpulmonarytuberculosisinfectionsandriskformultidrugresistancelimaperu
AT shicynthiax polyclonalpulmonarytuberculosisinfectionsandriskformultidrugresistancelimaperu
AT chindelevitchleonid polyclonalpulmonarytuberculosisinfectionsandriskformultidrugresistancelimaperu
AT calderonroger polyclonalpulmonarytuberculosisinfectionsandriskformultidrugresistancelimaperu
AT zhangzibiao polyclonalpulmonarytuberculosisinfectionsandriskformultidrugresistancelimaperu
AT galeajeromet polyclonalpulmonarytuberculosisinfectionsandriskformultidrugresistancelimaperu
AT contrerascarmen polyclonalpulmonarytuberculosisinfectionsandriskformultidrugresistancelimaperu
AT yatacorosa polyclonalpulmonarytuberculosisinfectionsandriskformultidrugresistancelimaperu
AT leccaleonid polyclonalpulmonarytuberculosisinfectionsandriskformultidrugresistancelimaperu
AT becerramercedesc polyclonalpulmonarytuberculosisinfectionsandriskformultidrugresistancelimaperu
AT murraymeganb polyclonalpulmonarytuberculosisinfectionsandriskformultidrugresistancelimaperu
AT cohented polyclonalpulmonarytuberculosisinfectionsandriskformultidrugresistancelimaperu

Ejemplares similares