Phylogenetic Analysis of Klebsiella pneumoniae from Hospitalized Children, Pakistan

Klebsiella pneumoniae shows increasing emergence of multidrug-resistant lineages, including strains resistant to all available antimicrobial drugs. We conducted whole-genome sequencing of 178 highly drug-resistant isolates from a tertiary hospital in Lahore, Pakistan. Phylogenetic analyses to place...

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Autores principales: Ejaz, Hasan, Wang, Nancy, Wilksch, Jonathan J., Page, Andrew J., Cao, Hanwei, Gujaran, Shruti, Keane, Jacqueline A., Lithgow, Trevor, ul-Haq, Ikram, Dougan, Gordon, Strugnell, Richard A., Heinz, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2017
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652443/
https://www.ncbi.nlm.nih.gov/pubmed/29048298
http://dx.doi.org/10.3201/eid2311.170833
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author Ejaz, Hasan
Wang, Nancy
Wilksch, Jonathan J.
Page, Andrew J.
Cao, Hanwei
Gujaran, Shruti
Keane, Jacqueline A.
Lithgow, Trevor
ul-Haq, Ikram
Dougan, Gordon
Strugnell, Richard A.
Heinz, Eva
author_facet Ejaz, Hasan
Wang, Nancy
Wilksch, Jonathan J.
Page, Andrew J.
Cao, Hanwei
Gujaran, Shruti
Keane, Jacqueline A.
Lithgow, Trevor
ul-Haq, Ikram
Dougan, Gordon
Strugnell, Richard A.
Heinz, Eva
author_sort Ejaz, Hasan
collection PubMed
description Klebsiella pneumoniae shows increasing emergence of multidrug-resistant lineages, including strains resistant to all available antimicrobial drugs. We conducted whole-genome sequencing of 178 highly drug-resistant isolates from a tertiary hospital in Lahore, Pakistan. Phylogenetic analyses to place these isolates into global context demonstrate the expansion of multiple independent lineages, including K. quasipneumoniae.
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spelling pubmed-56524432017-11-01 Phylogenetic Analysis of Klebsiella pneumoniae from Hospitalized Children, Pakistan Ejaz, Hasan Wang, Nancy Wilksch, Jonathan J. Page, Andrew J. Cao, Hanwei Gujaran, Shruti Keane, Jacqueline A. Lithgow, Trevor ul-Haq, Ikram Dougan, Gordon Strugnell, Richard A. Heinz, Eva Emerg Infect Dis Dispatch Klebsiella pneumoniae shows increasing emergence of multidrug-resistant lineages, including strains resistant to all available antimicrobial drugs. We conducted whole-genome sequencing of 178 highly drug-resistant isolates from a tertiary hospital in Lahore, Pakistan. Phylogenetic analyses to place these isolates into global context demonstrate the expansion of multiple independent lineages, including K. quasipneumoniae. Centers for Disease Control and Prevention 2017-11 /pmc/articles/PMC5652443/ /pubmed/29048298 http://dx.doi.org/10.3201/eid2311.170833 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Dispatch
Ejaz, Hasan
Wang, Nancy
Wilksch, Jonathan J.
Page, Andrew J.
Cao, Hanwei
Gujaran, Shruti
Keane, Jacqueline A.
Lithgow, Trevor
ul-Haq, Ikram
Dougan, Gordon
Strugnell, Richard A.
Heinz, Eva
Phylogenetic Analysis of Klebsiella pneumoniae from Hospitalized Children, Pakistan
title Phylogenetic Analysis of Klebsiella pneumoniae from Hospitalized Children, Pakistan
title_full Phylogenetic Analysis of Klebsiella pneumoniae from Hospitalized Children, Pakistan
title_fullStr Phylogenetic Analysis of Klebsiella pneumoniae from Hospitalized Children, Pakistan
title_full_unstemmed Phylogenetic Analysis of Klebsiella pneumoniae from Hospitalized Children, Pakistan
title_short Phylogenetic Analysis of Klebsiella pneumoniae from Hospitalized Children, Pakistan
title_sort phylogenetic analysis of klebsiella pneumoniae from hospitalized children, pakistan
topic Dispatch
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652443/
https://www.ncbi.nlm.nih.gov/pubmed/29048298
http://dx.doi.org/10.3201/eid2311.170833
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