Thermal sensitivity and flexibility of the Cε3 domains in immunoglobulin E

Immunoglobulin E (IgE) is the antibody that plays a central role in the mechanisms of allergic diseases such as asthma. Interactions with its receptors, FcεRI on mast cells and CD23 on B cells, are mediated by the Fc region, a dimer of the Cε2, Cε3 and Cε4 domains. A sub-fragment lacking the Cε2 dom...

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Detalles Bibliográficos
Autores principales: Doré, Katy A., Davies, Anna M., Drinkwater, Nyssa, Beavil, Andrew J., McDonnell, James M., Sutton, Brian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652521/
https://www.ncbi.nlm.nih.gov/pubmed/28844738
http://dx.doi.org/10.1016/j.bbapap.2017.08.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652521/
https://www.ncbi.nlm.nih.gov/pubmed/28844738
http://dx.doi.org/10.1016/j.bbapap.2017.08.005

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