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Severe steroid-resistant anti-PD1 T-cell checkpoint inhibitor-induced hepatotoxicity driven by biliary injury

INTRODUCTION: Hepatotoxicity from T-cell checkpoint blockade is an increasingly common immune-related adverse event, but remains poorly characterised and can be challenging to manage. Such toxicity is generally considered to resemble autoimmune hepatitis, although this assumption is extrapolated fro...

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Detalles Bibliográficos
Autores principales:	Doherty, Gary Joseph, Duckworth, Adam M, Davies, Susan E, Mells, George F, Brais, Rebecca, Harden, Susan V, Parkinson, Christine A, Corrie, Pippa G
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652580/ https://www.ncbi.nlm.nih.gov/pubmed/29081991 http://dx.doi.org/10.1136/esmoopen-2017-000268

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