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Thrombospondin-1 promotes cell migration, invasion and lung metastasis of osteosarcoma through FAK dependent pathway

Microenvironment at the metastatic locus usually differs greatly from that present in the site of primary tumor formation and it has a significant impact on the fate of the extravasated cancer cells. We compared gene expression signatures of primary tumors and lung metastatic tumors, and identified...

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Detalles Bibliográficos
Autores principales: Hu, Chuanzhen, Wen, Junxiang, Gong, Liangzhi, Chen, Xu, Wang, Jun, Hu, Fangqiong, Zhou, Qi, Liang, Jing, Wei, Li, Shen, Yuhui, Zhang, Weibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652671/
https://www.ncbi.nlm.nih.gov/pubmed/29100277
http://dx.doi.org/10.18632/oncotarget.17427