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Somatic mutations in salivary duct carcinoma and potential therapeutic targets

BACKGROUND: Salivary duct carcinomas (SDCa) are rare highly aggressive malignancies. Most patients die from distant metastatic disease within three years of diagnosis. There are limited therapeutic options for disseminated disease. RESULTS: 11 cases showed androgen receptor expression and 6 cases sh...

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Detalles Bibliográficos
Autores principales: Khoo, Timothy K., Yu, Bing, Smith, Joel A., Clarke, Angus J., Luk, Peter P., Selinger, Christina I., Mahon, Kate L., Kraitsek, Spiridoula, Palme, Carsten, Boyer, Michael J., Dinger, Marcel E., Cowley, Mark J., O’Toole, Sandra A., Clark, Jonathan R., Gupta, Ruta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652672/
https://www.ncbi.nlm.nih.gov/pubmed/29100278
http://dx.doi.org/10.18632/oncotarget.18173