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RECQ1 expression is upregulated in response to DNA damage and in a p53-dependent manner
Sensitivity of cancer cells to DNA damaging chemotherapeutics is determined by DNA repair processes. Consequently, cancer cells may upregulate the expression of certain DNA repair genes as a mechanism to promote chemoresistance. Here, we report that RECQ1, a breast cancer susceptibility gene that en...
Autores principales: | Parvathaneni, Swetha, Lu, Xing, Chaudhary, Ritu, Lal, Ashish, Madhusudan, Srinivasan, Sharma, Sudha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652675/ https://www.ncbi.nlm.nih.gov/pubmed/29100281 http://dx.doi.org/10.18632/oncotarget.18237 |
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