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Up-regulation of IRF-3 expression through GATA-1 acetylation by histone deacetylase inhibitor in lung adenocarcinoma A549 cells

Interferon regulatory factor 3 (IRF-3) is an important transcription factor for interferon genes. Although its functional activation by viral infection has been widely explicated, the regulatory mechanism of IRF-3 gene expression in cancer cells is poorly understood. In this study, we demonstrated t...

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Detalles Bibliográficos
Autores principales: Wang, Lu-Lu, Zhou, Lan-Bo, Shu, Jin, Li, Nan-Nan, Zhang, Hui-Wen, Jin, Rui, Zhuang, Li-Li, Zhou, Guo-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652676/
https://www.ncbi.nlm.nih.gov/pubmed/29100282
http://dx.doi.org/10.18632/oncotarget.18371