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Enhanced antitumor effect of biodegradable cationic heparin-polyethyleneimine nanogels delivering FILIP1LΔC103 gene combined with low-dose cisplatin on ovarian cancer

FILIP1LΔC103 (COOH terminal truncation mutant 1-790 of Filamin A Interacting Protein 1-Like) has been identified to hold therapeutic potential for suppressing tumor growth. Cisplatin (DDP) is commonly used as a first-line drug in the treatment for ovarian cancer. The usage of polymeric nanoparticles...

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Detalles Bibliográficos
Autores principales: Xie, Chuan, Gou, Maling, Yi, Tao, Qi, Xiaorong, Liu, Ping, Wei, Yuquan, Zhao, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652717/
https://www.ncbi.nlm.nih.gov/pubmed/29100323
http://dx.doi.org/10.18632/oncotarget.19464