Protective cellular immunity generated by cross-presenting recombinant overlapping peptide proteins

Priming of naive CD8(+) and CD4(+) T cells by dendritic cells (DCs) requires effective antigen presentation on both MHC class I and II molecules. We have developed a novel technology to use recombinant overlapping peptides (ROP) that stimulate both CD8(+) and CD4(+) T cell immune responses. The sing...

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Detalles Bibliográficos
Autores principales: Cai, Lili, Zhang, Jianbo, Zhu, Renying, Shi, Weixing, Xia, Xiaobing, Edwards, Mark, Finch, William, Coombs, Anthony, Gao, Ju, Chen, Kangwen, Owen, Sophie, Jiang, Shisong, Lu, Wenshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652724/
https://www.ncbi.nlm.nih.gov/pubmed/29100330
http://dx.doi.org/10.18632/oncotarget.20407

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