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The farnesoid X receptor negatively regulates osteoclastogenesis in bone remodeling and pathological bone loss

Farnesoid X receptor (FXR, NR1H4) is a member of the nuclear receptor superfamily of ligand-activated transcription factors. Since the role of FXR in osteoclast differentiation remains ill-defined, we investigated the biological function of FXR on osteoclastogenesis, using FXR-deficient mice. We dem...

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Detalles Bibliográficos
Autores principales:	Zheng, Ting, Kang, Ju-Hee, Sim, Jung-Sun, Kim, Jung-Woo, Koh, Jeong-Tae, Shin, Chan Soo, Lim, Hyungsik, Yim, Mijung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652726/ https://www.ncbi.nlm.nih.gov/pubmed/29100332 http://dx.doi.org/10.18632/oncotarget.20576

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