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Septin remodeling is essential for the formation of cell membrane protrusions (microtentacles) in detached tumor cells
Microtentacles are mostly microtubule-based cell protrusions that are formed by detached tumor cells. Here, we report that the formation of tumor cell microtentacles depends on the presence and dynamics of guanine nucleotide-binding proteins of the septin family, which are part of the cytoskeleton....
Autores principales: | Østevold, Kristine, Meléndez, Ana V., Lehmann, Friederike, Schmidt, Gudula, Aktories, Klaus, Schwan, Carsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652735/ https://www.ncbi.nlm.nih.gov/pubmed/29100341 http://dx.doi.org/10.18632/oncotarget.20805 |
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