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Targeting the HGF/c-MET pathway: stromal remodelling in pancreatic cancer
Stromal-tumor interactions in pancreatic cancer (PC) impact on treatment outcomes. Pancreatic stellate cells (PSCs) produce the collagenous stroma of PC and interact with cancer cells to facilitate disease progression. A candidate growth factor pathway that may mediate this interaction is the hepato...
Autores principales: | Pothula, Srinivasa P., Xu, Zhihong, Goldstein, David, Merrett, Neil, Pirola, Romano C., Wilson, Jeremy S., Apte, Minoti V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652738/ https://www.ncbi.nlm.nih.gov/pubmed/29100344 http://dx.doi.org/10.18632/oncotarget.20822 |
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