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PAX2 maintains the differentiation of mouse oviductal epithelium and inhibits the transition to a stem cell-like state

Recent studies have provided evidence that the secretory cells of the fallopian tube (oviduct) are a probable origin for high-grade serous ovarian carcinoma. In addition to secretory cells, the fallopian tube epithelium consists of ciliated cells and CD44+ undifferentiated stem-like cells. Loss of P...

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Detalles Bibliográficos
Autores principales: Alwosaibai, Kholoud, Abedini, Atefeh, Al-Hujaily, Ensaf M., Tang, Yong, Garson, Kenneth, Collins, Olga, Vanderhyden, Barbara C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652750/
https://www.ncbi.nlm.nih.gov/pubmed/29100356
http://dx.doi.org/10.18632/oncotarget.20173