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Ceramide-containing liposomes with doxorubicin: time and cell-dependent effect of C6 and C12 ceramide

Doxorubicin, a widely used chemotherapeutic drug, has several potential high-risk side effects including cardiomyopathy. Furthermore, cellular resistance to this drug develops with time. By using liposomes as carrier vesicles both the side effects and drug resistance might be avoided. In this study...

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Detalles Bibliográficos
Autores principales: Øverbye, Anders, Holsæter, Ann Mari, Markus, Fusser, Škalko-Basnet, Nataša, Iversen, Tore-Geir, Torgersen, Maria Lyngaas, Sønstevold, Tonje, Engebraaten, Olav, Flatmark, Kjersti, Mælandsmo, Gunhild Mari, Skotland, Tore, Sandvig, Kirsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652752/
https://www.ncbi.nlm.nih.gov/pubmed/29100358
http://dx.doi.org/10.18632/oncotarget.20217