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Chronically high level of tgfb1a induction causes both hepatocellular carcinoma and cholangiocarcinoma via a dominant Erk pathway in zebrafish

Liver cancers including both hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA) have increased steadily with the prevalence of non-alcoholic steatohepatitis (NASH), but the underlying mechanism for the transition from NASH to liver cancers remains unclear. Here we first employed diet-induce...

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Detalles Bibliográficos
Autores principales:	Yan, Chuan, Yang, Qiqi, Shen, Han-Ming, Spitsbergen, Jan M., Gong, Zhiyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652767/ https://www.ncbi.nlm.nih.gov/pubmed/29100373 http://dx.doi.org/10.18632/oncotarget.20357

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