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Combination therapy of human umbilical cord mesenchymal stem cells and FTY720 attenuates acute lung injury induced by lipopolysaccharide in a murine model

ALI/ARDS remain the main reason of morbidity and mortality in the critically ill. Studies have indicated that human umbilical cord mesenchymal stem cells (hUC-MSCs) can be useful in the treatment of ALI/ARDS. Sphingosine-1-phosphate (S1P) and its analog FTY720 significantly reduce lipopolysaccharide...

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Detalles Bibliográficos
Autores principales: Zhang, Zili, Li, Wenfei, Heng, Zhizhi, Zheng, Jing, Li, Puyuan, Yuan, Xin, Niu, Wenkai, Bai, Changqing, Liu, Huiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652788/
https://www.ncbi.nlm.nih.gov/pubmed/29100396
http://dx.doi.org/10.18632/oncotarget.20491