The E2F activators control multiple mitotic regulators and maintain genomic integrity through Sgo1 and BubR1

The E2F1, E2F2, and E2F3a transcriptional activators control proliferation. However, how the E2F activators regulate mitosis to maintain genomic integrity is unclear. Centrosome amplification (CA) and unregulated spindle assembly checkpoint (SAC) are major generators of aneuploidy and chromosome ins...

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Detalles Bibliográficos
Autores principales: Lee, Miyoung, Rivera-Rivera, Yainyrette, Moreno, Carlos S., Saavedra, Harold I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652806/
https://www.ncbi.nlm.nih.gov/pubmed/29100415
http://dx.doi.org/10.18632/oncotarget.20765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652806/
https://www.ncbi.nlm.nih.gov/pubmed/29100415
http://dx.doi.org/10.18632/oncotarget.20765

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