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Pyrimidine metabolic rate limiting enzymes in poorly-differentiated hepatocellular carcinoma are signature genes of cancer stemness and associated with poor prognosis

Cellular metabolism of cancer cell is generally recognized to provide energy for facilitating tumor growth, but little is known about the aberrant metabolism in tumor progression and its prognostic value. Here, we applied integrated genomic approach to uncover the aberrant expression of metabolic en...

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Detalles Bibliográficos
Autores principales: Yeh, Hsi-Wen, Lee, Szu-Shuo, Chang, Chieh-Yu, Hu, Chun-Mei, Jou, Yuh-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652811/
https://www.ncbi.nlm.nih.gov/pubmed/29100421
http://dx.doi.org/10.18632/oncotarget.20774