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Effect of TALEN-mediated IL-6 knockout on cell proliferation, apoptosis, invasion and anti-cancer therapy in hepatocellular carcinoma (HCC-LM3) cells

PURPOSE: To determine the exact effect of Interleukin-6 (IL-6) on tumor cell proliferation, apoptosis, invasion, and anti-cancer therapy in hepatocellular carcinoma (HCC). EXPERIMENTAL DESIGN: IL-6 was disrupted by transcription activator-like effector nucleases (TALEN) in HCCLM3 cells, and was used...

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Detalles Bibliográficos
Autores principales:	Zhuang, Peng-Yuan, Zhang, Ke-Wei, Wang, Jian-Dong, Zhou, Xue-Ping, Liu, Ying-Bin, Quan, Zhi-Wei, Shen, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652824/ https://www.ncbi.nlm.nih.gov/pubmed/29100435 http://dx.doi.org/10.18632/oncotarget.20946

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