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Inhibition of miR-142-5P ameliorates disease in mouse models of experimental colitis

BACKGROUND: MicroRNAs (miRNAs) are epigenetically involved in regulating gene expression. They may be of importance in the pathogenesis of inflammatory bowel disease (IBD). The aim of this study was to determine the role of miRNAs by their specific blocking in the CD4+CB45RB(hi) T-cell transfer mode...

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Detalles Bibliográficos
Autores principales:	Duijvis, Nicolette W., Moerland, Perry D., Kunne, Cindy, Slaman, Monique M. W., van Dooren, Faas H., Vogels, Esther W., de Jonge, Wouter J., Meijer, Sybren L., Fluiter, Kees, te Velde, Anje A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653202/ https://www.ncbi.nlm.nih.gov/pubmed/29059189 http://dx.doi.org/10.1371/journal.pone.0185097

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