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Inter-dependent apical microtubule and actin dynamics orchestrate centrosome retention and neuronal delamination

Detachment of newborn neurons from the neuroepithelium is required for correct neuronal architecture and functional circuitry. This process, also known as delamination, involves adherens-junction disassembly and acto-myosin-mediated abscission, during which the centrosome is retained while apical/ci...

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Detalles Bibliográficos
Autores principales: Kasioulis, Ioannis, Das, Raman M, Storey, Kate G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653239/
https://www.ncbi.nlm.nih.gov/pubmed/29058679
http://dx.doi.org/10.7554/eLife.26215