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Evaluation of a novel biodegradable thermosensitive keto-hydrogel for improving postoperative pain in a rat model

This study evaluates the sustained analgesic effect of ketorolac-eluting thermosensitive biodegradable hydrogel in the plantar incisional pain model of the rat hind-paw. A ketorolac-embedded 2, 2'-Bis (2-oxazolin) (BOX) linking methoxy-poly(ethylene glycol) and poly(lactide-co-glycolide) (mPEG-...

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Detalles Bibliográficos
Autores principales:	Wu, Meng-Huang, Shih, Ming-Hung, Hsu, Wei-Bin, Dubey, Navneet Kumar, Lee, Wen-Fu, Lin, Tsai-Yu, Hsieh, Meng-Yow, Chen, Chin-Fu, Peng, Kuo-Ti, Huang, Tsung-Jen, Shi, Chung-Sheng, Guo, Ren-Shyang, Cai, Chang-Jhih, Chung, Chiu-Yen, Wong, Chung-Hang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653328/ https://www.ncbi.nlm.nih.gov/pubmed/29059223 http://dx.doi.org/10.1371/journal.pone.0186784

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