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Identification of two immortalized cell lines, ECV304 and bEnd3, for in vitro permeability studies of blood-brain barrier

To identify suitable cell lines for a mimetic system of in vivo blood-brain barrier (BBB) for drug permeability assessment, we characterized two immortalized cell lines, ECV304 and bEnd3 in the respect of the tightness, tight junction proteins, P-glycoprotein (P-gp) function and discriminative brain...

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Detalles Bibliográficos
Autores principales:	Yang, Shu, Mei, Shenghui, Jin, Hong, Zhu, Bin, Tian, Yue, Huo, Jiping, Cui, Xu, Guo, Anchen, Zhao, Zhigang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653355/ https://www.ncbi.nlm.nih.gov/pubmed/29059256 http://dx.doi.org/10.1371/journal.pone.0187017

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