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New horizons in hypoxia signaling pathways
Investigation into the regulation of the erythropoietin gene by oxygen led to the discovery of a process of direct oxygen sensing that transduces many cellular and systemic responses to hypoxia. The oxygen-sensitive signal is generated through the catalytic action of a series of 2-oxoglutarate-depen...
Autores principales: | Pugh, Christopher W., Ratcliffe, Peter J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653532/ https://www.ncbi.nlm.nih.gov/pubmed/28315322 http://dx.doi.org/10.1016/j.yexcr.2017.03.008 |
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