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Validation of the Arabic version of the Functional Assessment of Cancer Therapy-Bladder questionnaire in Egyptian patients with bladder cancer

OBJECTIVES: To validate the Arabic version of the Functional Assessment of Cancer Therapy-Bladder (FACT-Bl) questionnaire in Egyptian patients who underwent radical cystectomy (RC) and orthotopic neobladder (ONB) construction. PATIENTS, SUBJECTS AND METHODS: The English version of the FACT-Bl was tr...

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Autores principales: Zahran, Mohamed H., Sheir, Khaled, Zidan, Essam M., Ali-El-Dein, Bedeir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653643/
https://www.ncbi.nlm.nih.gov/pubmed/29071139
http://dx.doi.org/10.1016/j.aju.2017.01.008
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author Zahran, Mohamed H.
Sheir, Khaled
Zidan, Essam M.
Ali-El-Dein, Bedeir
author_facet Zahran, Mohamed H.
Sheir, Khaled
Zidan, Essam M.
Ali-El-Dein, Bedeir
author_sort Zahran, Mohamed H.
collection PubMed
description OBJECTIVES: To validate the Arabic version of the Functional Assessment of Cancer Therapy-Bladder (FACT-Bl) questionnaire in Egyptian patients who underwent radical cystectomy (RC) and orthotopic neobladder (ONB) construction. PATIENTS, SUBJECTS AND METHODS: The English version of the FACT-Bl was translated into the Arabic language using multi-step process by two urologist and two independent translators. The Arabic version was validated by inviting 90 patients who underwent RC and ONB and 72 normal individuals to complete the questionnaire. The reliability of the questionnaire was tested for internal consistency using the Cronbach’s α test. Inter-domain association was tested by Spearman’s correlation coefficient. The discrimination validity was measured by comparing the scores in RC patients and in normal individuals using the Mann–Whitney U-test and independent sample t-test. RESULTS: Internal consistency was high for all domains. There was high correlation between all domains. This high internal consistency and good correlation was maintained when assessment included patients with <7.5 and those with ≥7.5 years follow-up. Discrimination validation was confirmed by the statistically significant lower scores of all domains in the studied patients in comparison to the controls. CONCLUSION: The Arabic version of the FACT-Bl is a reliable and validated instrument that can be used to evaluate health-related quality of life in patients after RC and ONB.
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spelling pubmed-56536432017-10-25 Validation of the Arabic version of the Functional Assessment of Cancer Therapy-Bladder questionnaire in Egyptian patients with bladder cancer Zahran, Mohamed H. Sheir, Khaled Zidan, Essam M. Ali-El-Dein, Bedeir Arab J Urol Oncology/Reconstruction OBJECTIVES: To validate the Arabic version of the Functional Assessment of Cancer Therapy-Bladder (FACT-Bl) questionnaire in Egyptian patients who underwent radical cystectomy (RC) and orthotopic neobladder (ONB) construction. PATIENTS, SUBJECTS AND METHODS: The English version of the FACT-Bl was translated into the Arabic language using multi-step process by two urologist and two independent translators. The Arabic version was validated by inviting 90 patients who underwent RC and ONB and 72 normal individuals to complete the questionnaire. The reliability of the questionnaire was tested for internal consistency using the Cronbach’s α test. Inter-domain association was tested by Spearman’s correlation coefficient. The discrimination validity was measured by comparing the scores in RC patients and in normal individuals using the Mann–Whitney U-test and independent sample t-test. RESULTS: Internal consistency was high for all domains. There was high correlation between all domains. This high internal consistency and good correlation was maintained when assessment included patients with <7.5 and those with ≥7.5 years follow-up. Discrimination validation was confirmed by the statistically significant lower scores of all domains in the studied patients in comparison to the controls. CONCLUSION: The Arabic version of the FACT-Bl is a reliable and validated instrument that can be used to evaluate health-related quality of life in patients after RC and ONB. Elsevier 2017-04-25 /pmc/articles/PMC5653643/ /pubmed/29071139 http://dx.doi.org/10.1016/j.aju.2017.01.008 Text en © 2017 Arab Association of Urology. Production and hosting by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Oncology/Reconstruction
Zahran, Mohamed H.
Sheir, Khaled
Zidan, Essam M.
Ali-El-Dein, Bedeir
Validation of the Arabic version of the Functional Assessment of Cancer Therapy-Bladder questionnaire in Egyptian patients with bladder cancer
title Validation of the Arabic version of the Functional Assessment of Cancer Therapy-Bladder questionnaire in Egyptian patients with bladder cancer
title_full Validation of the Arabic version of the Functional Assessment of Cancer Therapy-Bladder questionnaire in Egyptian patients with bladder cancer
title_fullStr Validation of the Arabic version of the Functional Assessment of Cancer Therapy-Bladder questionnaire in Egyptian patients with bladder cancer
title_full_unstemmed Validation of the Arabic version of the Functional Assessment of Cancer Therapy-Bladder questionnaire in Egyptian patients with bladder cancer
title_short Validation of the Arabic version of the Functional Assessment of Cancer Therapy-Bladder questionnaire in Egyptian patients with bladder cancer
title_sort validation of the arabic version of the functional assessment of cancer therapy-bladder questionnaire in egyptian patients with bladder cancer
topic Oncology/Reconstruction
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653643/
https://www.ncbi.nlm.nih.gov/pubmed/29071139
http://dx.doi.org/10.1016/j.aju.2017.01.008
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