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Dynamics of lineage commitment revealed by single-cell transcriptomics of differentiating embryonic stem cells
Gene expression heterogeneity in the pluripotent state of mouse embryonic stem cells (mESCs) has been increasingly well-characterized. In contrast, exit from pluripotency and lineage commitment have not been studied systematically at the single-cell level. Here we measure the gene expression dynamic...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5653659/ https://www.ncbi.nlm.nih.gov/pubmed/29061959 http://dx.doi.org/10.1038/s41467-017-01076-4 |